Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sirt1  sirtuin 1   (Synonyms: Sir2, Sir2alpha)
Results	Reference
1	J:330211 Hwang YJ, Sung GJ, Marquardt R, Young SL, Lessey BA, Kim TH, Cheon YP, Jeong JW, SIRT1 plays an important role in implantation and decidualization during mouse early pregnancy. Biol Reprod. 2022 Jun 13;106(6):1072-1082
1	J:151680 Iwahara N, Hisahara S, Hayashi T, Horio Y, Transcriptional activation of NAD+-dependent protein deacetylase SIRT1 by nuclear receptor TLX. Biochem Biophys Res Commun. 2009 Sep 4;386(4):671-5
1	J:297808 Li B, Li M, Li X, Li H, Lai Y, Huang S, He X, Si X, Zheng H, Liao W, Liao Y, Bin J, Sirt1-inducible deacetylation of p21 promotes cardiomyocyte proliferation. Aging (Albany NY). 2019 Dec 26;11(24):12546-12567
1	J:307395 Mirra S, Garcia-Arroyo R, B Domenech E, Gavalda-Navarro A, Herrera-Ubeda C, Oliva C, Garcia-Fernandez J, Artuch R, Villarroya F, Marfany G, CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina. Neurobiol Dis. 2021 Aug;156:105405
1*	J:172620 Ogawa T, Wakai C, Saito T, Murayama A, Mimura Y, Youfu S, Nakamachi T, Kuwagata M, Satoh K, Shioda S, Distribution of the longevity gene product, SIRT1, in developing mouse organs. Congenit Anom (Kyoto). 2011 Jun;51(2):70-9
1*	J:87352 Sakamoto J, Miura T, Shimamoto K, Horio Y, Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain. FEBS Lett. 2004 Jan 2;556(1-3):281-6
1	J:180628 Seifert EL, Caron AZ, Morin K, Coulombe J, Hong He X, Jardine K, Dewar-Darch D, Boekelheide K, Harper ME, McBurney MW, SirT1 catalytic activity is required for male fertility and metabolic homeostasis in mice. FASEB J. 2012 Feb;26(2):555-66
1*	J:120915 Tanno M, Sakamoto J, Miura T, Shimamoto K, Horio Y, Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1. J Biol Chem. 2007 Mar 2;282(9):6823-32
1	J:321746 Yu H, Zhang F, Yan P, Zhang S, Lou Y, Geng Z, Li Z, Zhang Y, Xu Y, Lu Y, Chen C, Wang D, Zhu W, Hu X, Wang J, Zhuang T, Zhang Y, Wu G, Liu J, Zeng C, Pu WT, Sun K, Zhang B, LARP7 Protects Against Heart Failure by Enhancing Mitochondrial Biogenesis. Circulation. 2021;143(20):2007-2022